22 March 2022

Shipping Vaccines and Biologics with Refrigeration

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Cooled Solutions

Cooled Solutions · Nederlandse producent

Shipping Vaccines and Biologics with Refrigeration

Cool Shipping of Vaccines and Biological Medicines

The transport of vaccines and biological medicines is one of the most regulated activities within pharmaceutical logistics. Temperature ranges are strict, and the consequences of exceeding them can be serious.

Standard Temperature Ranges

2 – 8 °C: most vaccines, insulins, biologicals
15 – 25 °C: controlled room temperature
-20 °C: some mRNA vaccines
-70 °C: deep freeze for specific vaccines (dry ice required)

GDP Compliance is Mandatory

GDP guidelines apply to the distribution of medicines. Key elements:

Qualified packaging solutions (with test data)
Continuous temperature monitoring during transport
Complete documentation of transport conditions
Procedures for temperature deviations
Validated preparation times for packages

The Right Packaging Solution

For 2-8 °C shipments (the most common requirement) we offer:

EPS boxes with validated insulation value
Special conditioned gel packs (not frozen ice — too cold!)
Temperature loggers for monitoring during transport
Insulating bottom sheets and top layers

Important: Preconditioning

Conditioned gel packs must acclimate at room temperature for several hours before use. Packs that are too cold can damage vaccines by freezing. Always follow the validated procedure.